Summary of Systematic Reviews on Clinical Outcomes of Submucosal Tunnel Endoscopic Resection (STER) for Treatment of Subepithelial Tumors
Author | Search period | Studies included | No. of cases | Follow-up duration (mo) | Mean tumor size (cm) | Mean operative time (min) | Complete resection rate (%) | En-bloc resection rate (%) | Tumor recurrence (%) | Complication |
---|---|---|---|---|---|---|---|---|---|---|
Jain et al (2017)34 | Up to February 2016 | 16 studies: -4 prospective -9 retrospective -3 case reports |
703 patients | 1–32 | 2.1 (0.6–5.5) | Esophageal or EGJ lesions: 120.1 (15–365) | 99.8 | 92.1 | 0 | 272 adverse events (37.0%) -Air leak: 1 (0.1%) -Bleeding: 6 (0.8%) -Chest pain: 4 (0.5%) -Esophageal diverticulum: 2 (0.2%) -Esophageal pleural fistula: 1 (0.1%) -Mucosal injury/laceration: 4 (0.5%) -Perforation: 17 (2.3%) -Pneumomediastinum: 16 (2.2%) -Pneumoperitoneum: 19 (2.6%) -Pneumothorax: 44 (6.0%) -Subcutaneous emphysema: 101 (13.7%) -Subphrenic infection: 1 (0.1%) -Thoracic/pleural effusion: 56 (7.6%) |
736 lesions: -465 esophageal -146 EGJ -125 gastric |
Gastric lesions: 86.7 (25–320) | |||||||||
Lv et al (2017)35 | Up to November 2015 | 28 studies: -8 prospective -20 retrospective |
1,041 patients | 7.1 (1.9–18.0) |
1.9 (0.5–7) | 55.8 | 97.5 | 94.6 | 0 | 263 adverse events -Bleeding: 8 -Perforation: 18 (5.6%) -Pneumoperitoneum: 42 (6.8%) -Pneumothorax: 48 (6.1%) -Subcutaneous emphysema and pneumomediastinum: 147 (14.8%) |
1,085 lesions: -712 esophageal -95 EGJ -141 cardia -137 gastric |
Values are presented as mean (range).
EGJ, esophagogastric junction.
*Median of mean follow-up (range).