pISSN 2636-0004
eISSN 2636-0012

Table. 2.

Summary of Systematic Reviews on Clinical Outcomes of Submucosal Tunnel Endoscopic Resection (STER) for Treatment of Subepithelial Tumors

Author Search period Studies included No. of cases Follow-up duration (mo) Mean tumor size (cm) Mean operative time (min) Complete resection rate (%) En-bloc resection rate (%) Tumor recurrence (%) Complication
Jain et al (2017)34 Up to February 2016 16 studies:
-4 prospective
-9 retrospective
-3 case reports
703 patients 1–32 2.1 (0.6–5.5) Esophageal or EGJ lesions: 120.1 (15–365) 99.8 92.1 0 272 adverse events (37.0%)
-Air leak: 1 (0.1%)
-Bleeding: 6 (0.8%)
-Chest pain: 4 (0.5%)
-Esophageal diverticulum: 2 (0.2%)
-Esophageal pleural fistula: 1 (0.1%)
-Mucosal injury/laceration: 4 (0.5%)
-Perforation: 17 (2.3%)
-Pneumomediastinum: 16 (2.2%)
-Pneumoperitoneum: 19 (2.6%)
-Pneumothorax: 44 (6.0%)
-Subcutaneous emphysema: 101 (13.7%)
-Subphrenic infection: 1 (0.1%)
-Thoracic/pleural effusion: 56 (7.6%)
736 lesions:
-465 esophageal
-146 EGJ
-125 gastric
Gastric lesions: 86.7 (25–320)
Lv et al (2017)35 Up to November 2015 28 studies:
-8 prospective
-20 retrospective
1,041 patients 7.1 (1.9–18.0)* 1.9 (0.5–7) 55.8 97.5 94.6 0 263 adverse events
-Bleeding: 8
-Perforation: 18 (5.6%)
-Pneumoperitoneum: 42 (6.8%)
-Pneumothorax: 48 (6.1%)
-Subcutaneous emphysema and pneumomediastinum: 147 (14.8%)
1,085 lesions:
-712 esophageal
-95 EGJ
-141 cardia
-137 gastric

Values are presented as mean (range).

EGJ, esophagogastric junction.

*Median of mean follow-up (range).

Int J Gastrointest Interv 2020;9:42~52 https://doi.org/10.18528/ijgii200007
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