Selected Studies Reporting the Outcomes of Flexible Endoscopic Myotomy in Zenker’s Diverticulum
Study | Number | Age (yr) |
Size (cm) |
Knife | Procedure time (min) |
Adverse event |
Recurrence/success |
Follow-up (mo) |
---|---|---|---|---|---|---|---|---|
Vogelsang et al (2007)4 | 31 | 69 (52–92) | 3.7 | Needle knife | NR | 23% (minor) | Recurrence: 39% (single treatment) | 26 (14–49) |
Al-Kadi et al (2010)5 | 18 | 80 (68–91) | NR | Needle knife | 28.4 (10–60) | 1 (microperforation) | Recurrence: 2 | 27.5 (0.5–84) |
Repici et al (2010)6 | 32 | 74.8 | < 3: 6 | Hook knife | 28 (22–45) | 6.25% | Success: 90.6% | 23.87 ± 9.6 |
3–4: 10 | ||||||||
> 4: 16 | ||||||||
Case and Baron (2010)7 | 22 | 84.5 (59–96) | NR | Needle knife | NR | 27% (perforation) | Success: 82% | 12.7 ± 9.2 |
Huberty et al (2013)8 | 150 | 73 (42–94) | 3 (1–8) | Needle knife | NR | 2.2% | Recurrence: 23.1% | 43 (13–121) |
Battaglia et al (2015)9 | 31 | 71 (52–85) | 3 (1–8) | Stag Beetle (SB) knife | 14 (11–23) | 1 (bleeding) | Recurrence: 2 | 7 (2–18) |
Halland et al (2016)10 | 52 | 77 (34–97) | 2.8 (1–5) | Needle knife and Hook knife | NR | Mild: 16% | Recurrence: 23% | 26 (0.5–68) |
Moderate: 2% | ||||||||
Severe: 2% | ||||||||
Brueckner et al (2016)11 | 46 | 67 (40–85) | NR | Hook knife | NR | Bleeding: 3 | Recurrence: 30% | 39 (18–73) |
Emphysema: 1 | ||||||||
Costamagna et al (2016)12 | 89 | 70 (42–94) | 3.0 (1.5–11) | Needle knife | 15 (7–45) | Perforation: 2% | Recurrence: 36% | 32 (1–98) |
Bleeding: 1% | ||||||||
Goelder et al (2016)13 | 52 | 71 (42–86) | 3 (1–5) | SB knife | 32 (18–60) | No major complication | Success: 90% (single session) | 16 (2–31) |
Pescarus et al (2016)14 | 26 | 74.9 (47.3–96.7) | 2.8 (1–5) | Needle or Hook knife | 68 (28–149) | Leak: 1 patient | Recurrence: 11.5% | 21.8 (1–68.2) |
Dişibeyaz et al (2017)15 | 17 | 65.3 | 3.2 (2–5) | Needle knife | NR | 17.6% | Recurrence: 23.5% | 47.7 (14–104) |
Rath et al (2018)16 | 21 | 74.9 (47.3–96.7) | 1.5–5.6 | Clutch Cutter | 19 (CC) | Minor bleed: 1 | Recurrence: 1 | 12 |
CC: 6 | Needle knife | 43 (NK) | Delayed bleed: 1 | |||||
NK: 15 | Cervical emphysema: 3 | |||||||
Fan et al (2019)17 | 9 | 77 (66–85) | NR | Needle knife | 36 (14–65) | None | Recurrence: 7 | 11 (2–46) |
Diez Redondo et al (2019)18 | 69 | 73.4 (46–93) | 2.8 (1–5) | Ligasure | 22 (11–48) | Microperforation: 2.5 | Success: 84% | 34.6 (24–64) |
Delayed bleed: 1.3 |
CC, clutch cutter; NK, needle knife; NR, not reported.
*Values are presented as median (range) or mean only unless otherwise indicated.
†Values are presented as percent or number.