Current Techniques for the Endoscopic Management of Zenker’s Diverticulum
Procedure characteristic | Conventional technique | Double incision and snare resection32,33 | Z-POEM/STESD41,42 |
---|---|---|---|
Procedure duration (min) | 14–68 | 28–56 | 13.8–52.4 |
Success (%) | 60–100 | 96–100 | 92–95 |
Advantages | Largest data on outcomes, technically not demanding, major adverse events, short procedure duration, uncommon, recurrences can be treated with same technique | High success rate, low recurrence rate, no special accessory required | Essentially similar to POEM, good efficacy, low rate of adverse events, complete division of septum can be achieved |
Drawbacks | High recurrence after single treatment, technique not standardized | Difficult in shallow/small diverticulum, limited data (only two studies), long term results remain to be seen | Limited data, technical difficulty if not performing submucosal endoscopy, pouch mucosa not cut which may lead to recurrences, no comparative studies |
Z-POEM, Zenker’s per-oral endoscopic myotomy; STESD, submucosal tunneling endoscopic submucosal dissection.