Adverse Events during Submucosal Tunnelling Endoscopic Resection (Selected Studies)
Study | No. of patients/type of study | Location of SET (n) | Size, range (cm) | Adverse events |
---|---|---|---|---|
Ye et al (2014)31 | 85/prospective | Esophagus = 60 | 1.9 (1.0–3.0) | Total = 8 (9.4) |
Cardia = 16 | Pneumothorax = 6 (7.1) | |||
Stomach = 9 | Subcutaneous emphysema = 8 (9.4) | |||
Pneumoperitoneum = 4 (4.7) | ||||
Chen et al (2016)5 | 290/retrospective | Esophagus = 199 | 2.1 (1.0–7.0) | Total = 68 (23.4) |
Esophagogastric junction = 68 | Subcutaneous emphysema = 61 (21) | |||
Stomach = 23 | Pneumothorax = 22 (7.6) (drainage = 3.1) | |||
Pneumoperitoneum = 15 (5.2) | ||||
Mucosal injury = 3 (1) (clipping) | ||||
Major bleeding = 5 (1.7) (endoscopic coagulation) | ||||
Thoracic effusion = 49 (16.9) (drainage = 3.8) | ||||
Esophageal pleural fistula = 1 (0.3) (clipping) | ||||
Mao et al (2017)32 | 56/prospective | Location of cardia tumor | 1.8 (1.0–3.2) | Total = 9 (15.3) |
Above GE junction = 18 | Subcutaneous emphysema = 9 (15.3) | |||
Below GE junction = 38 | Pneumoperitoneum = 9 (15.3) | |||
Pneumothorax = 8 (14.3) | ||||
Pleural effusion = 5 (8.9) | ||||
Du et al (2019)33 | 165/retrospective | Upper esophagus = 49 | 2 (0.5–8) | Total = 35 (21) |
Middle esophagus = 46 | Esophageal tumor = 21 (19.8) | |||
Cardia = 59 | Cardia tumor = 14 (23.7) | |||
Gas related complication = 16 (9.7) | ||||
Fever = 10 (6) | ||||
Mucosal injury = 10 (6) | ||||
Chest/abdominal pain = 4 (2.4) | ||||
Pleural effusion = 1 (0.6) | ||||
Perforation = 1 (0.6) |
SET, subepithelial tumor; GE, gastroesophageal.
*Values are presented as number (%). More than one events patients.