pISSN 2636-0004eISSN 2636-0012
pISSN 2636-0004Adverse Events during Gastric Peroral Endoscopic Myotomy (Selected Studies)
| Study | No. of patients/type of study | Adverse events |
Follow-up (mo) |
|---|---|---|---|
| Shlomovitz et al (2015)41 | 7/retrospective | Total = 3 (42.8) | 6.5 |
| Bleeding within 2 wk-pyloric ulcer-clipping done = 1 (14.2) | |||
| Dysphagia = 1 (14.2) | |||
| Hospital acquired pneumonia = 1 (14.2) | |||
| Gonzalez et al (2017)42 | 29/retrospective | Total = 11 (37.9) | 10 |
| Pneumoperitoneum-needle decompression = 5 (17) | |||
| Moderate abdominal pain-analgesics = 3 (10) | |||
| Bleeding-spontaneously stopped = 1 (3) | |||
| Abscess with bleeding (clipping) = 1 (3) | |||
| Stricture-endoscopic radial incision (insulated tip knife) = 1 (3) | |||
| Rodriguez et al (2018)43 | 100/prospective | Total = 10 (10) | 3 |
| Capnoperitoneum and subcutaneous emphysema requiring diagnostic laparoscopy = 1 (1) | |||
| GI bleeding (2 mucosal ulcer, 2 source not identified) = 4 (4) | |||
| Severe dehydration = 2 (2) | |||
| Upper GI endoscopy within 30 days = 3 (3) | |||
| Death within 30 days-cardiac cause = 1 (1) | |||
| Kahaleh et al (2018)44 | 33/multicentre retrospective | Total = 2 (6.1) | 11.5 |
| Ulcer (mucosal defect)-clip placement = 1 (3) | |||
| Procedural bleeding-managed with coagrasper = 1 (3) | |||
| Mekaroonkamol et al (2019)45 | 40/retrospective | Total = 3 (7.5) | 18 |
| Capnoperitoneum = 1 (2.5) | |||
| Chronic obstructive pulmonary disease exacerbation = 1 (2.5) | |||
| Mucosectomy closure site disruption = 1 (2.5) | |||
| Jacques et al (2019)46 | 20/prospective | Total 28 adverse events in 16 patients (80%) | 3 |
| 20 Related events, 8 Unrelated events | |||
| 5 Major events | |||
| Perforation with severe pain requiring laparoscopy = 1 (5) | |||
| Abdelfatah et al (2020)47 | 90/retrospective | Total = 2 (2.2) | 3–6 |
| Single myotomy = 55 | Tension pneumoperitoneum-needle decompression = 1 (1.1) | ||
| Double myotomy = 35 | Mucosectomy site ulcer bleed-endoscopic intervention = 1 (1.1) |
GI, gastrointestinal.
*Values are presented as number (%).