pISSN 2636-0004eISSN 2636-0012
pISSN 2636-0004Results of Endoscopic Retrograde Cholangiopancreatography-Guided Intraductal Radiofrequency Ablation in Pancreatobiliary Tumor
| Author (year) | Patients ( |
Diagnosis ( |
Type of stents ( |
Median stent patency (day) |
Median survival (mo) |
Median no. of RFA |
No. of adverse events (%) |
|---|---|---|---|---|---|---|---|
| Steel et al (2011)22 | 22 | BDC 6 PDAC 16 |
Uncovered SEMS 21 | 114 | NA | 2 | 4/21 (19.0) Cholecystitis 2 Pancreatitis 1 Rigor 1 |
| Figueroa-Barojas et al (2013)23 | 20 | BDC 11 PDAC 7 Others 2 |
Uncovered SEMS 1 Partially/fully covered SEMS 13 Plastic stent 6 |
NA | NA | NA | 5/20 (25.0) Pancreatitis 1 Cholecystitis 1 Pain 5 |
| Alis et al (2013)24 | 17 | BDC | Fully covered SEMS 10 | 270 | NA | 3 | 2/10 (20.0) Pancreatitis 2 |
| Dolak et al (2014)15 | 58 | BDC (Klatskin 45) Others 13 |
SEMS 35 Plastic stent 19 |
171 | 10.6 | 1.4 | 11/58 (19.0) Liver infarction 1 Hemobilia 3 GB empyema 1 Cholangitis 5 Sepsis 2 Hepatic coma 1 Left bundle branch block 1 |
| Tal et al (2014)14 | 12 | BDC (Klatskin 9) Others 3 |
Plastic stent 12 | NA | 6.4 | 1.5 | 6/12 (50.0) Hemobilia 4 Mortality 2 |
| Sharaiha et al (2014)29 | 26 | BDC 18 PDAC 8 |
Uncovered SEMS 7 Covered SEMS 8 Plastic stent 11 |
NA | 5.9 | NA | 5/26 (19.2) Pancreatitis 1 Cholangitis 1 Pain 3 |
| Sharaiha et al (2015)16 | 69 | BDC 45 PDAC 19 GBC 2 Others 4 |
SEMS 49 Plastic stent 20 |
NA | 11.5 | 1.4 | 7/69 (10.1) Pancreatitis 1 Cholecystitis 2 Hemobilia 1 Pain 3 |
| Kallis et al (2015)25 | 23 | Unresectable PDAC | Uncovered SEMS 23 | 324 | 7.5 | NA | 2/23 (8.7) Hyperamylasemia 1 Cholangitis 1 |
| Laquière et al (2016)26 | 12 | BDC (Klatskin 12) | SEMS or plastic stent | NA | 12.3 | 1.6 | 2/12 (16.7) Cholangitis 1 Sepsis 1 |
| Wang et al (2016)27 | 12 | BDC 9 Others 3 |
SEMS or plastic stent | 125 | 7.7 | 1.67 | 1/12 (8.3) Pancreatitis 1 |
| Schmidt et al (2016)28 | 14 | BDC 14 Others 2 |
SEMS or Plastic stent | NA | NA | 2.2 | 4/14 (28.6) Cholangitis 2 Liver abscess 2 |
| Laleman et al (2017)17 | 18 | PDAC 7 BDC (Klatskin 11) |
SEMS or Plastic stent | 110 | 7.6 | 1 | 6/18 (33.3) Cholangitis 4 Pancreatitis 2 |
| Yang et al (2018)18 | 32 | BDC (distal 22, Klatskin 10) | Plastic stent | 195 | 13.2 | NA | 2/32 (6.3) Cholangitis 2 |
| Lee et al (2019)19 | 30 | BDC 19 PDAC 9 GBC 2 |
Uncovered SEMS 10 Covered SEMS 20 |
236 | 12.8 | NA | 3/30 (10.0) Pancreatitis 2 Cholangitis 1 |
| Kim et al (2019)20 | 11 | BDC (Klatskin 8) GBC 2 Others 1 |
Uncovered SEMS 10 Plastic stent 1 |
91 | NA | 4 (2-8) | 6/12 (50.0) Pancreatitis 1 Post-procedural fever 5 |
| Bokemeyer et al (2019)30 | 32 | BDC (distal 1, Klatskin 23) PDAC 2 GBC 2 Others 4 |
SEMS or Plastic stent | NA | 11.4 | 1.68 | 10 (31.3) Cholangitis 6 Pancreatitis 2 Intestinal perforation 1 Pneumothorax 1 |
| Hu et al (2020)33 | 23 | Ampullary cancer 23 | SEMS or Plastic stent | NA | 36.0 | 2.26 | 4 (7.7) Mild pancreatitis 1 Bleeding 1 Late distal biliary stenosis 2 |
| Gao et al (2020)31 | 87 | BDC (Klatskin 69) Ampullary cancer 18 |
Plastic stent | NA | 14.3 | 1 | 24 (27.6) Pancreatitis 4 Bleeding 1 Cholangitis 10 Cholecystitis 9 |
| Yang et al (2020)32 | 38 | BDC (distal 26, Klatskin 12) | Plastic stent | 168 | 11.0 | 1 | 4 (10.5) Cholangitis 2 Pancreatitis 1 Bleeding 1 |
RFA, radiofrequency ablation; BDC, bile duct cancer; PDAC, pancreatic ductal adenocarcinoma; GBC, gallbladder cancer; SEMS, self-expandable metallic stent.