International Journal of Gastrointestinal Intervention

Table. 3. Table 3

Univariate Kaplan-Meier and Cox Analysis Overall Survival in Months

Variable	P-value	Hazard ratio	Median survival	95% confidence interval
Overall survival			40.9	33.394–48.339
Age^*	0.028	1.035		1.004–1.068
Pre-TIPS MELD score^*	0.049	1.068		1.000–1.141
Post-TIPS MELD score^*	0.005	1.082		1.024–1.143
Sex	0.932
Female			46.4	39.115–53.645
Male			39.9	15.991–63.743
Presence of VT	0.085
Venous thrombosis			47.7	30.942–64.339
Patent veins			24.7	5.061–44.339
Causes of cirrhosis
Alcoholic hepatitis	0.517		39.9	8.104–71.630
HCV	0.739		46.4	21.631–71.169
NASH/NAFLD	0.965		39.8	4.262–75.338
PBC^†	0.807		-	-
Wilson disease^†	0.055		5.4	-
Autoimmune hepatitis^†	0.473		-	-
Alcoholic and HCV	0.695		15.5	0.000–37.257
Cryptogenic	0.942		40.9	39.225–42.508
Indications for TIPS
Refractory ascites	0.311		40.9	29.112–52.622
Variceal bleeding^†	0.093		58.0	-
Hydrothorax	0.584		26.2	9.694–42.706
Budd-Chiari syndrome^†	0.029		5.4	-
Multifactorial	0.695		11.1	0.000–37.257
Shunt diameter	0.695
8 mm			39.9	16.557–63.176
10 mm			46.4	25.980–66.820
Encephalopathy at 90 days	0.071
Yes			39.8	7.635–71.965
No			47.7	33.924–61.409
Liver infarct	0.200
Yes			26.2	0.000–58.621
No			46.4	38.985–53.815
Portal and hepatic bed thrombosis
Right posterior portal vein	0.691		40.2	29.057–51.277
Right anterior portal vein^†	0.600		-	-
Right portal vein^†	0.059		51.3	-
Main portal vein	< 0.001		1.1	0.000–4.171
Left portal vein	0.716		58.0	0.000–135.002
Superior mesenteric vein^†	< 0.001		1.1	-
Middle hepatic vein	0.500		15.6	0.000–61.954
Right hepatic vein^†	0.258		40.2	-

TIPS, transjugular intrahepatic portosystemic shunt; MELD, Model for End-Stage Liver Disease; VT, vein thrombosis; HCV, hepatitis C virus; NASH, non-alcoholic steatohepatitis; NAFLD, nonalcoholic fatty liver disease; PBC, primary biliary cholangitis.

^*Hazard ratio with 95% confidence intervals reported.

^†Greater than 50% of the data are censored, and the standard error and confidence intervals were indeterminate.

Int J Gastrointest Interv 2022;11:18~23 https://doi.org/10.18528/ijgii210028