pISSN 2636-0004eISSN 2636-0012
pISSN 2636-0004A Summary of Optimal EUS-Guided Tissue Acquisition and Processing Methods
| Needle shape | Franseen, fork-tip, and Menghini-tip needles are all recommended. Through-the-needle microforceps are promising for pancreatic cysts. |
| Needle gauge | A 22-gauge needle is recommended considering its convenience and clinical evidence. The 19-gauge needle seems to be in the spotlight again because more tissue is better for genetic profiling. |
| Tissue acquisition technique | Rapid insertion and slow withdrawal of needle under negative suction, 15 times. The fanning technique or torque technique. |
| Confirmation of adequacy of the obtained sample | Macroscopic on-site evaluation to confirm histologic core. |
| Cytology preparation | Liquid-based cytology (SurePath). |
| Ancillary test | Addition of molecular profiling. |
EUS, endoscopic ultrasound.