Adverse Events Reported in Previous Studies
Author (year) | Number | Ablative agent | Adverse event | |||
---|---|---|---|---|---|---|
Rate (%) | Details ( |
Mild to moderate | Severe | |||
EUS-guided ethanol ablation | ||||||
Gan et al11 (2005) | 23 | E | 0 | 0 | 0 | |
DiMaio et al12 (2011) | 13 | E | 8 | Abdominal pain (1) | 1 | 0 |
Caillol et al19 (2012) | 13 | E | 0 | 0 | 0 | |
Park et al16 (2016) | 91 | E | 23.1 | Abdominal pain (18) Acute pancreatitis (3) |
21 | 0 |
Gómez et al15 (2016) | 23 | E | 8.7 | Acute pancreatitis (1) Abdominal pain (1) |
1 | 1 |
Choi et al28 (2019) | 214 | E | 33.2 | Abdominal pain (70) Acute pancreatitis (21) Duodenal stricture (2) Bleeding (1) Cholangitis (1) |
27 | 3 |
EUS-guided ablation Including chemotherapeutic agents | ||||||
Oh et al13 (2011) | 52 | E + P | 9 | Fever (1) Acute pancreatitis (1) Abdominal pain (1) Pericystic spillage (1) Splenic vein obstruction (1) |
5 | 0 |
DeWitt et al14 (2014) | 21 | E + P | 75 | Abdominal pain (4) Acute pancreatitis (3) Peritonitis (1) Gastric wall cyst (1) |
5 | 4 |
Choi et al17 (2017) | 164 | E + P | 9 | Acute pancreatitis (6) Pseudocyst (2) Abscess (2) Portal vein thrombosis (1) Fever (1) Splenic vein obstruction (1) Pancreatic duct stricture (1) Pericystic spillage (1) Intracystic hemorrhage (1) |
15 | 1 |
Kim et al23 (2017) | 8 | E | 25 | Abdominal pain (4) Acute pancreatitis (4) Intracystic hemorrhage (1) |
5 | 4 |
28 | E + P | |||||
Moyer et al25 (2017) | 18 | E + G + P | 28 | Abdominal pain (4) Acute pancreatitis (1) |
4 | 1 |
21 | G + P | 0 | 0 | 0 |
EUS, endoscopic ultrasound; E, ethanol; P, paclitaxel; G, gemcitabine.