Characteristics of the Studies on EUS-CGN and EUS-BPN
Reference | Year | Design | Number | Technique | Pain relief (follow-up time) |
Complication |
---|---|---|---|---|---|---|
Levy et al38 | 2008 | Retrospective | 17 | CGN | 94% (4 week) | Diarrhea 16%, hypotension 35%, transient pain 41% |
Ascunce et al1 | 2011 | Retrospective | 64 | CGN vs CPN | 65% vs 25% (1 week) | Diarrhea 23%, hypotension 2%, transient pain 2% |
Doi et al17 | 2013 | RCT | 68 | CGN vs CPN | 73% vs 45% (1 week) | Diarrhea 5.9% vs 9.1%, hypotension 2.9% vs 6%, pain 29.4% vs 21.2% |
Ishiwatari et al14 | 2014 | Retrospective | 22 | CGN/CPN | 83% (fenol) vs 69% (ethanol) (1 week) | Diarrhea 9%, hypotension 4.5%, burning pain 4.5%, inebriation 4.5% |
Si-Jie et al39 | 2014 | Retrospective | 41 | CGN vs CPN | 80% vs 80% (3–90 day) | Hypotension 4.9% |
Levy et al24 | 2019 | RCT | 110 | CGN + CPN vs CPN | 46% vs 40% (12 week) | Transient pain 8.3% vs 44.9%, neurolytic effect 23.3% vs 55.1% |
Sakamoto et al41 | 2010 | Retrospective | 67 | BPN vs CPN | NA | None |
Minaga et al42 | 2016 | Retrospective | 64 | BPN | 77% (1 week), 67% (4 week) | Diarrhea 3.6%, hypotension 4.5%, pain 3.6%, inebriation 8% |
EUS-CGN, endoscopic ultrasound-guided celiac ganglia neurolysis; EUS-BPN, endoscopic ultrasound-guided broad plexus neurolysis; CPN, celiac plexus neurolysis; RCT, randomized controlled trials; NA, not available.