Factors Associated with the Occurrence of Post-ERCP Pancreatitis
Variable | Univariate analysis | Multivariate model | |||||||
---|---|---|---|---|---|---|---|---|---|
OR | 95% CI for OR | Adjusted OR | 95% CI for OR | ||||||
Lower | Upper | Lower | Upper | ||||||
Age (18–40 yr) | 0.64 | 0.14 | 2.91 | 0.57 | NA | ||||
Age (41–60 yr) | 0.74 | 0.21 | 2.72 | 0.65 | NA | ||||
Female | 4.2 | 0.52 | 9.56 | 0.17 | 1.1 | 0.88 | 2.67 | 0.54 | |
Smoking | 0.96 | 0.25 | 3.73 | 0.96 | NA | ||||
Alcohol | 2.64 | 0.27 | 25.61 | 0.21 | 2.13 | 1.12 | 3.02 | < 0.05 | |
Normal bilirubin (≤ 1 mg/dL) | 0.84 | 0.26 | 2.64 | 0.17 | 0.44 | 0.21 | 1.84 | 0.72 | |
> 1 pancreatic duct guidewire cannulation | 3.2 | 1.01 | 10.17 | < 0.05 | 2.81 | 1.79 | 4.52 | < 0.05 | |
Biliary sphincterotomy | 0.78 | 0.09 | 6.77 | 0.82 | NA | ||||
Failure to remove all stones | 2.32 | 0.65 | 8.26 | 0.19 | 1.45 | 0.87 | 2.05 | 0.44 | |
Plastic biliary stent | 1.1 | 0.13 | 9.26 | 0.93 | NA | ||||
Difficult cannulation | 3.45 | 1.08 | 11.04 | < 0.05 | 1.42 | 0.69 | 2.36 | 0.62 | |
Needle knife sphincterotomy | 3.39 | 1.04 | 10.99 | < 0.05 | 0.58 | 0.31 | 2.54 | 0.34 | |
Non-dilated common bile duct | 0.51 | 0.15 | 1.64 | 0.26 | NA | ||||
Self-expandable metal stents | 2.64 | 0.27 | 14.6 | 0.41 | NA | ||||
Common bile duct stone | 0.49 | 0.12 | 1.99 | 0.32 | NA | ||||
Common bile duct tumor | 1.81 | 0.35 | 9.1 | 0.47 | NA | ||||
No hydration | 0.87 | 0.25 | 3.01 | 0.83 | NA |