Association of Variables with Overall Survival
No. of patients ( |
Overall survival |
|||||||
---|---|---|---|---|---|---|---|---|
1-year (%) | 3-year (%) | 5-year (%) | 7-year (%) | Median | 95% CI | |||
Technique | 0.697 | |||||||
MWA | 33 | 100 | 72.6 | 62.2 | 41.5 | 59.39 (4.90) | 49.78–68.99 | |
RFA | 31 | 96.8 | 69.5 | 57.9 | 50.2 | 61.00 (5.01) | 51.17–70.83 | |
K-ras oncogene | < 0.001 | |||||||
Wild-type | 34 | 97.1 | 88.0 | 80.7 | 70.6 | 71.55 (4.13) | 63.45–79.66 | |
Mutated | 30 | 100 | 53.1 | 38.1 | 22.9 | 48.81 (4.82) | 39.36–58.25 | |
Prior systemic chemotherapy |
0.613 | |||||||
No | 39 | 97.4 | 73.5 | 64.4 | 47.5 | 62.60 (4.28) | 54.21–70.99 | |
Yes | 25 | 100 | 67.8 | 53.8 | 47.0 | 57.49 (5.87) | 45.98–69.00 | |
Colorectal localization | 0.025 | |||||||
Right | 16 | 93.8 | 62.5 | 50.0 | 12.5 | 49.22 (6.39) | 36.68–61.75 | |
Left/rectum | 48 | 100 | 74.0 | 64.0 | 57.0 | 64.13 (3.93) | 56.41–71.85 | |
Lung metastasis | < 0.001 | |||||||
No | 49 | 100 | 87.4 | 75.7 | 59.4 | 70.03 (3.10) | 63.95–76.12 | |
Yes | 15 | 93.3 | 17.8 | 0.0 | 0.0 | 26.49 (3.18) | 20.26–32.73 | |
LTP during follow-up | < 0.001 | |||||||
No | 49 | 85.0 | 61.0 | 52.2 | 45.2 | 66.94 (4.32) | 58.46–75.43 | |
Yes | 15 | 53.3 | 25.0 | 0.0 | 0.0 | 51.10 (5.28) | 40.74–61.45 |
CI, confidence interval; MWA, microwave ablation; RFA, radiofrequency ablation; LTP, local tumor progression.
*Prior systemic chemotherapy choice was neoadjuvant in all patients (see Table 1).
†Median survival is shown on a monthly basis, while annual survival is shown as a percentage. Values in parentheses are the standard error values.
‡Log-rank comparisons between variables.