International Journal of Gastrointestinal Intervention

Table. 2. Table 2

Cox Proportional-Hazard Analysis of the Risk Factors for Adverse Disease-Free Survival and Overall Survival Outcomes

Factor	Disease-free survival				Overall survival

	Univariate		Multivariate		Univariate		Multivariate

	HR (95% CI)	P-value	Adjusted-HR (95% CI)	P-value	HR (95% CI)	P-value	Adjusted-HR (95% CI)	P-value
LR (vs. TACE-LR)	1.03 (0.60–1.79)	0.904	1.19 (0.66–2.12)	0.568	1.22 (0.45–3.33)	0.692	1.60 (0.56–4.54)	0.380
Number of tumors	1.55 (0.96–2.51)	0.074	1.67 (1.04–2.7)	0.034	2.42 (1.2–4.88)	0.013	3.53 (1.60–7.79)	0.002
Size of tumor	1.05 (0.98–1.13)	1.183			1.09 (1.00–1.20)	0.053
MELD score	1.03 (0.94–1.13)	0.553			0.92 (0.74–1.15)	0.489
AFP > 200 (vs. < 200)	1.86 (1.14–3.03)	0.012	1.69 (1.02–2.79)	0.04	2.23 (0.96–5.18)	0.062
Major hepatectomy (vs. minor)	0.84 (0.48–1.48)	0.549			2.08 (0.89–4.87)	0.093
Operative time ≥ 360 min (vs. < 360)	1.53 (0.92–0.56)	0.103			1.42 (0.55–3.63)	0.469
Blood loss ≥ 500 mL (vs. < 500)	1.83 (1.11–3.01)	0.018	1.75 (1.01–3.04)	0.047	4.74 (1.40–16.04)	0.012	4.87 (1.37–17.30)	0.014
LPPRC transfusion intraoperatively	2.05 (1.27–3.30)	0.003	1.78 (0.21–6.53)	0.844	1.21 (0.69–2.11)	0.512
FFP transfusion intraoperatively	2.46 (1.41–4.28)	0.001	1.91 (1.03–3.52)	0.039	3.35 (1.40–8.01)	0.007	3.38 (1.31–8.72)	0.012
Postoperative complications (vs. no complication)	1.2 (0.63–2.29)	0.575			2.44 (0.99–5.99)	0.052
Biliary leakage/fistula	2.22 (0.81–6.12)	0.122			2.67 (0.78–9.15)	0.119
Grade of differentiation; poorly differentiation (vs. well/moderate)	1.33 (0.78–2.27)	0.294			2.00 (0.83–4.83)	0.121
Lymphovascular invasion	1.02 (0.32–3.25)	0.978			0.89 (0.21–3.84)	0.881

Int J Gastrointest Interv 2023;12:169~175 https://doi.org/10.18528/ijgii230025